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Differential role of NR2A and NR2B subunits in NMDA receptor antagonist-induced aberrant cortical gamma oscillations

BACKGROUND: NMDA receptor (NMDA-R) hypofunction plays an important role in cognitive impairment in schizophrenia. NMDA-R antagonists elicit psychotic symptoms in human and schizophrenia-relevant signs in rodents, including a strong increase in cortical gamma activity. NMDA-Rs are composed of differe...

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Detalhes bibliográficos
Autor principal: Kocsis, Bernat
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3276718/
https://ncbi.nlm.nih.gov/pubmed/22055014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2011.10.002
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