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Retinoic Acid and Affective Disorders: The Evidence for an Association

OBJECTIVE: Isotretinoin (13-cis-retinoic acid, or 13-cis-RA) (Accutane), approved by the FDA for the treatment of acne, carries a black box warning related to the risk of depression, suicide, and psychosis. Retinoic acid (RA), the active form of vitamin A, regulates gene expression in the brain, and...

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Bibliografiske detaljer
Main Authors: Bremner, J Douglas, Shearer, Kirsty, McCaffery, Peter
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3276716/
https://ncbi.nlm.nih.gov/pubmed/21903028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4088/JCP.10r05993
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