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Age-Related Somatic Structural Changes in the Nuclear Genome of Human Blood Cells
Structural variations are among the most frequent interindividual genetic differences in the human genome. The frequency and distribution of de novo somatic structural variants in normal cells is, however, poorly explored. Using age-stratified cohorts of 318 monozygotic (MZ) twins and 296 single-bor...
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Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Elsevier
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3276669/ https://ncbi.nlm.nih.gov/pubmed/22305530 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2011.12.009 |
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