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Fixation Probability in a Two-Locus Model by the Ancestral Recombination–Selection Graph

We use the ancestral influence graph (AIG) for a two-locus, two-allele selection model in the limit of a large population size to obtain an analytic approximation for the probability of ultimate fixation of a single mutant allele A. We assume that this new mutant is introduced at a given locus into...

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Main Authors: Lessard, Sabin, Kermany, Amir R.
格式: Artigo
語言:Inglês
出版: Genetics Society of America 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3276620/
https://ncbi.nlm.nih.gov/pubmed/22095080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.111.136309
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