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Using Functional Signatures to Identify Repositioned Drugs for Breast, Myelogenous Leukemia and Prostate Cancer

The cost and time to develop a drug continues to be a major barrier to widespread distribution of medication. Although the genomic revolution appears to have had little impact on this problem, and might even have exacerbated it because of the flood of additional and usually ineffective leads, the em...

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Detalles Bibliográficos
Main Authors: Shigemizu, Daichi, Hu, Zhenjun, Hung, Jui-Hung, Huang, Chia-Ling, Wang, Yajie, DeLisi, Charles
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3276504/
https://ncbi.nlm.nih.gov/pubmed/22346740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002347
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