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Rifampicin inhibition of RNA synthesis by destabilisation of DNA-RNA polymerase-oligonucleotide-complexes.

Although the antibiotic rifampicin inhibits the transcription of poly[d(A-T)] by E.coli RNA polymerase, a series of short oligonucleotides is produced. It is claimed that the overall inhibition of RNA synthesis by rifampicin is caused by a destabilising effect on the binding of the intermediate olig...

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Autori principali: Schulz, W, Zillig, W
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1981
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC327649/
https://ncbi.nlm.nih.gov/pubmed/6174947
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