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Identification of a new plasma biomarker of Alzheimer's disease using metabolomics technology

We performed unbiased analysis of steroid-related compounds to identify novel Alzheimer's disease (AD) plasma biomarkers using liquid chromatography-atmospheric pressure chemical ionization-mass spectroscopy. The analysis revealed that desmosterol was found to be decreased in AD plasma versus c...

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Autori principali: Sato, Yoshiaki, Suzuki, Ikumi, Nakamura, Tatsuji, Bernier, Francois, Aoshima, Ken, Oda, Yoshiya
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Biochemistry and Molecular Biology 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3276481/
https://ncbi.nlm.nih.gov/pubmed/22203775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M022376
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