Liver Patt1 deficiency protects male mice from age-associated but not high-fat diet-induced hepatic steatosis

Patt1 is a newly identified protein acetyltransferase that is highly expressed in liver. However, the role of Patt1 in liver is still unclear. We generated Patt1 liver-specific knockout (LKO) mice and mainly measured the effect of hepatic Patt1 deficiency on lipid metabolism. Hepatic Patt1 deficienc...

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Main Authors: Liu, Yang, Zhou, Daizhan, Zhang, Fang, Tu, Yanyang, Xia, Yulei, Wang, Hui, Zhou, Ben, Zhang, Yi, Wu, Jingxia, Gao, Xiang, He, Zhishui, Zhai, Qiwei
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Biochemistry and Molecular Biology 2012
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3276459/
https://ncbi.nlm.nih.gov/pubmed/22231784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M019257
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