Type I diabetes mellitus decreases in vivo macrophage-to-feces reverse cholesterol transport despite increased biliary sterol secretion in mice

Type I diabetes mellitus (T1DM) increases atherosclerotic cardiovascular disease; however, the underlying pathophysiology is still incompletely understood. We investigated whether experimental T1DM impacts HDL-mediated reverse cholesterol transport (RCT). C57BL/6J mice with alloxan-induced T1DM had...

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Main Authors: Freark de Boer, Jan, Annema, Wijtske, Schreurs, Marijke, van der Veen, Jelske N., van der Giet, Markus, Nijstad, Niels, Kuipers, Folkert, Tietge, Uwe J. F.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3276458/
https://ncbi.nlm.nih.gov/pubmed/22180634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M018671
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