Multiplex Chromosomal Exome Sequencing Accelerates Identification of ENU-Induced Mutations in the Mouse

Forward genetic screens in Mus musculus have proved powerfully informative by revealing unsuspected mechanisms governing basic biological processes. This approach uses potent chemical mutagens, such as N-ethyl-N-nitrosourea (ENU), to randomly induce mutations in mice, which are then bred and phenoty...

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Bibliografiset tiedot
Päätekijät: Sun, Miao, Mondal, Kajari, Patel, Viren, Horner, Vanessa L., Long, Alyssa B., Cutler, David J., Caspary, Tamara, Zwick, Michael E.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Genetics Society of America 2012
Aiheet:
Investigation
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3276189/
https://ncbi.nlm.nih.gov/pubmed/22384391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.111.001669
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