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A Synthetic Human Kinase Can Control Cell Cycle Progression in Budding Yeast

The DDK kinase complex, composed of Cdc7 and Dbf4, is required for S-phase progression. The two component proteins show different degrees of sequence conservation between human and yeast. Here, we determine that Saccharomyces cerevisiae bearing human CDC7 and DBF4 grows comparably to cells with yeas...

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Detalhes bibliográficos
Main Authors: Davey, Megan J., Andrighetti, Heather J., Ma, Xiaoli, Brandl, Christopher J.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3276143/
https://ncbi.nlm.nih.gov/pubmed/22384342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.111.000430
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