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Novel anti-Cryptosporidium activity of known drugs identified by high-throughput screening against parasite fatty acyl-CoA binding protein (ACBP)

BACKGROUND: Cryptosporidium parvum causes an opportunistic infection in AIDS patients, and no effective treatments are yet available. This parasite possesses a single fatty acyl-CoA binding protein (CpACBP1) that is localized to the unique parasitophorous vacuole membrane (PVM). The major goal of th...

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Bibliografiske detaljer
Main Authors: Fritzler, Jason M., Zhu, Guan
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3276058/
https://ncbi.nlm.nih.gov/pubmed/22167242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkr516
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