In situ photochemical crosslinking of HeLa cell mitochondrial DNA by a psoralen derivative reveals a protected region near the origin of replication.
The in vivo association with proteins of HeLa cell mitochondrial DNA (mtDNA) has been investigated by analyzing the pattern of in situ crosslinking of the DNA by 4'-hydroxymethyl-4, 5',8-trimethylpsoralen (HMT). Either isolated mitochondria or whole cells were irradiated with long wavelength UV ligh...
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| 發表在: | Nucleic Acids Res |
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| Principais autores: | , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Oxford University Press
1981
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC327581/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6273818/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/9.22.6017 |
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