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Anti-CD137 mAb Deletes Both Donor CD4(+) and CD8(+) T Cells in Acute Graft-versus-host Disease

We previously demonstrated that in vivo engagement of CD137, a member of TNF receptor superfamily, can delete allorective CD4(+) T cells through the induction of activation-induced cell death (AICD) in chronic graft-versus-host disease (cGVHD) and subsequently reverse established cGVHD. In this stud...

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Detalhes bibliográficos
Main Authors: Kim, Juyang, Cho, Hong Rae, Kwon, Byungsuk
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Association of Immunologists 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3275716/
https://ncbi.nlm.nih.gov/pubmed/22346787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4110/in.2011.11.6.428
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