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Rapid Insulinotropic Action of Low Doses of Bisphenol-A on Mouse and Human Islets of Langerhans: Role of Estrogen Receptor β

Bisphenol-A (BPA) is a widespread endocrine-disrupting chemical (EDC) used as the base compound in the manufacture of polycarbonate plastics. It alters pancreatic β-cell function and can be considered a risk factor for type 2 diabetes in rodents. Here we used ERβ−/− mice to study whether ERβ is invo...

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Détails bibliographiques
Auteurs principaux: Soriano, Sergi, Alonso-Magdalena, Paloma, García-Arévalo, Marta, Novials, Anna, Muhammed, Sarheed J., Salehi, Albert, Gustafsson, Jan-Ake, Quesada, Ivan, Nadal, Angel
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3275611/
https://ncbi.nlm.nih.gov/pubmed/22347437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031109
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