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Shortening of 3′UTRs Correlates with Poor Prognosis in Breast and Lung Cancer

A major part of the post-transcriptional regulation of gene expression is affected by trans-acting elements, such as microRNAs, binding the 3′ untraslated region (UTR) of their target mRNAs. Proliferating cells partly escape this type of negative regulation by expressing shorter 3′ UTRs, depleted of...

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Detalhes bibliográficos
Main Authors: Lembo, Antonio, Di Cunto, Ferdinando, Provero, Paolo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3275581/
https://ncbi.nlm.nih.gov/pubmed/22347440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031129
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