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Determining PTEN Functional Status by Network Component Deduced Transcription Factor Activities
PTEN-controlled PI3K-AKT-mTOR pathway represents one of the most deregulated signaling pathways in human cancers. With many small molecule inhibitors that target PI3K-AKT-mTOR pathway being exploited clinically, sensitive and reliable ways of stratifying patients according to their PTEN functional s...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3275574/ https://ncbi.nlm.nih.gov/pubmed/22347425 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031053 |
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