Intraovarian Thrombin and Activated Protein C Signaling System Regulates Steroidogenesis during the Periovulatory Period

In addition to its role in blood coagulation, thrombin directly stimulates protease-activated receptors (PAR) or interacts with thrombomodulin (THBD) to activate membrane-bound protein C which stimulates PAR1 and PAR4 receptors to promote downstream pleiotropic effects. Our DNA microarray, RT-PCR, a...

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Autores principales: Cheng, Yuan, Kawamura, Kazuhiro, Deguchi, Masashi, Takae, Seido, Mulders, Sabine M., Hsueh, Aaron J. W.
Formato: Artigo
Lenguaje:Inglês
Publicado: Endocrine Society 2012
Materias:
Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3275165/
https://ncbi.nlm.nih.gov/pubmed/22207716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2011-1187
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