Identification and suppression of secondary structures formed from deoxy-oligonucleotides during electrophoresis in denaturing polyacrylamide-gels.

Nature and stability of secondary structures formed from DNA-fragments during electrophoresis in urea containing polyacrylamide-gels were investigated. Duplices and especially hairpin loops were found to be surprisingly stable. Polyacrylamide-gels containing high concentrations of formamide effectiv...

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Pubblicato in:	Nucleic Acids Res
Autori principali:	Frank, R, Müller, D, Wolff, C
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Oxford University Press 1981
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC327492/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7312623/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/9.19.4967
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