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Interaction between Mouse Adenovirus Type 1 and Cell Surface Heparan Sulfate Proteoglycans

Application of human adenovirus type 5 (Ad5) derived vectors for cancer gene therapy has been limited by the poor cell surface expression, on some tumor cell types, of the primary Ad5 receptor, the coxsackie-adenovirus-receptor (CAR), as well as the accumulation of Ad5 in the liver following interac...

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Detalhes bibliográficos
Main Authors: Lenaerts, Liesbeth, van Dam, Wim, Persoons, Leentje, Naesens, Lieve
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3274534/
https://ncbi.nlm.nih.gov/pubmed/22347482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031454
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