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Non-canonical wnt Signals Antagonize and Canonical wnt Signals Promote Cell Proliferation in Early Kidney Development

Canonical and non-canonical wnt signals often have opposed roles. In this report, we use developing Xenopus embryos to demonstrate a novel anti-proliferative role for non-canonical wnt signals in the very earliest stages of kidney development. Non-canonical wnt signals were down-regulated using PDZ...

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Detalhes bibliográficos
Main Authors: Mccoy, Kyle E., Zhou, Xiaolan, Vize, Peter D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3274170/
https://ncbi.nlm.nih.gov/pubmed/21465621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.22626
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