Single-Cell Mass Cytometry of Differential Immune and Drug Responses Across a Human Hematopoietic Continuum

Flow cytometry is an essential tool for dissecting the functional complexity of hematopoiesis. We used single-cell “mass cytometry” to examine healthy human bone marrow, measuring 34 parameters simultaneously in single cells (binding of 31 antibodies, viability, DNA content, and relative cell size)....

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Detalhes bibliográficos
Main Authors: Bendall, Sean C., Simonds, Erin F., Qiu, Peng, Amir, El-ad D., Krutzik, Peter O., Finck, Rachel, Bruggner, Robert V., Melamed, Rachel, Trejo, Angelica, Ornatsky, Olga I., Balderas, Robert S., Plevritis, Sylvia K., Sachs, Karen, Pe’er, Dana, Tanner, Scott D., Nolan, Garry P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3273988/
https://ncbi.nlm.nih.gov/pubmed/21551058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1198704
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