Inhibition of the Ca(2+) release channel, IP(3)R subtype 3 by caffeine slows glioblastoma invasion and migration and extends survival

Ca(2+) signaling is an important determining factor in many cellular processes, especially in cancer cell proliferation, motility and invasion. Glioblastoma is the deadliest brain cancer with its average survival time of less than a year, with the most prominent cellular feature being the ability of...

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Bibliografiske detaljer
Main Authors: Kang, Sang Soo, Han, Kyung-Seok, Ku, Bo Mi, Lee, Yeon Kyung, Hong, Jinpyo, Shin, Hye Young, Almonte, Antoine G., Woo, Dong Ho, Brat, Daniel J., Hwang, Eun Mi, Yoo, Seung Hyun, Chung, Chun Kee, Park, Sung-Hye, Paek, Sun Ha, Roh, Eun Joo, Lee, Sung joong, Park, Jae-Yong, Traynelis, Stephen F., Lee, C. Justin
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3273964/
https://ncbi.nlm.nih.gov/pubmed/20103623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-2886
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