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Relationship of spindle assembly checkpoint fidelity to species body mass, lifespan, and developmental rate

We have examined the tolerance of the spindle assembly checkpoint (SAC), as measured by the appearance of tetraploid cells in the presence of a microtubule inhibitor, in a series of primary cell strains derived from species with diverse lifespan and body size. We find that the integrity of the SAC v...

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Bibliografske podrobnosti
Main Authors: Lorenzini, Antonello, Fink, Lauren S., Stamato, Thomas, Torres, Claudio, Sell, Christian
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3273901/
https://ncbi.nlm.nih.gov/pubmed/22201071
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