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Oligoclonal antibody targeting ghrelin increases energy expenditure and reduces food intake in fasted mice

Ghrelin, an enteric peptide hormone linked to the pathophysiology of obesity has been a therapeutic target of great interest over the past decade. Many research efforts have focused on the antagonism of ghrelin’s endogenous receptor GHSR1a, which is found along ascending vagal afferent fibers, as we...

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Bibliografiske detaljer
Main Authors: Zakhari, Joseph S., Zorrilla, Eric P., Zhou, Bin, Mayorov, Alexander V., Janda, Kim D.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3273630/
https://ncbi.nlm.nih.gov/pubmed/22149064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp200376c
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