Probing the Helical Tilt and Dynamic Properties of Membrane-bound Phospholamban in Magnetically Aligned Bicelles Using Electron Paramagnetic Resonance Spectroscopy

Wild-type Phospholamban (WT-PLB), a Ca(2+)-ATPase (SERCA) regulator in the sarcoplasmic reticulum membrane, was studied using TOAC nitroxide spin labeling, magnetically aligned bicelles, and electron paramagnetic resonance (EPR) spectroscopy to ascertain structural and dynamic information. Different...

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Detalhes bibliográficos
Main Authors: Ghimire, Harishchandra, Abu-Baker, Shadi, Sahu, Indra D., Zhou, Andy, Mayo, Daniel J., Lee, Ryan. T., Lorigan, Gary. A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3273594/
https://ncbi.nlm.nih.gov/pubmed/22172806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2011.11.030
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