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Activation of the NLRP3 inflammasome by group B streptococci

Group B streptococcus (GBS) is a frequent agent of life-threatening sepsis and meningitis in neonates and adults with predisposing conditions. We tested the hypothesis that activation of the inflammasome, an inflammatory signaling complex, is involved in host defenses against this pathogen. We show...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Costa, Alessandro, Gupta, Rahul, Signorino, Giacomo, Malara, Antonio, Cardile, Francesco, Biondo, Carmelo, Midiri, Angelina, Galbo, Roberta, Trieu-Cuot, Patrick, Papasergi, Salvatore, Teti, Giuseppe, Henneke, Philipp, Mancuso, Giuseppe, Golenbock, Douglas T., Beninati, Concetta
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3273589/
https://ncbi.nlm.nih.gov/pubmed/22250086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102543
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