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BIODEGRADABLE NANOPARTICLES MIMICKING PLATELET BINDING AS A TARGETED AND CONTROLLED DRUG DELIVERY SYSTEM

This research aims to develop targeted nanoparticles as drug carriers to the injured arterial wall under fluid shear stress by mimicking the natural binding ability of platelets via interactions of glycoprotein Ib-alpha (GP Ibα) of platelets with P-selectin of damaged endothelial cells (ECs) and/or...

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Detalhes bibliográficos
Main Authors: Kona, Soujanya, Dong, Jing-Fei, Liu, Yaling, Tan, Jifu, Nguyen, Kytai T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3273581/
https://ncbi.nlm.nih.gov/pubmed/22172292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2011.11.043
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