The double-stranded break-forming activity of plant SPO11s and a novel rice SPO11 revealed by a Drosophila bioassay

BACKGROUND: SPO11 is a key protein for promoting meiotic recombination, by generating chromatin locus- and timing-specific DNA double-strand breaks (DSBs). The DSB activity of SPO11 was shown by genetic analyses, but whether SPO11 exerts DSB-forming activity by itself is still an unanswered question...

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Detalhes bibliográficos
Main Authors: Shingu, Yoshinori, Tokai, Takeshi, Agawa, Yasuo, Toyota, Kentaro, Ahamed, Selina, Kawagishi-Kobayashi, Makiko, Komatsu, Akira, Mikawa, Tsutomu, Yamamoto, Masa-Toshi, Wakasa, Kyo, Shibata, Takehiko, Kusano, Kohji
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3273433/
https://ncbi.nlm.nih.gov/pubmed/22248237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-13-1
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