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Mechanism of nucleotide sensing in group II chaperonins

Group II chaperonins mediate protein folding in an ATP-dependent manner in eukaryotes and archaea. The binding of ATP and subsequent hydrolysis promotes the closure of the multi-subunit rings where protein folding occurs. The mechanism by which local changes in the nucleotide-binding site are commun...

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Autores principales: Pereira, Jose H, Ralston, Corie Y, Douglas, Nicholai R, Kumar, Ramya, Lopez, Tom, McAndrew, Ryan P, Knee, Kelly M, King, Jonathan A, Frydman, Judith, Adams, Paul D
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3273386/
https://ncbi.nlm.nih.gov/pubmed/22193720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.468
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