Polyinosinic:polycytidylic acid induces protein kinase D–dependent disassembly of apical junctions and barrier dysfunction in airway epithelial cells

BACKGROUND: Disruption of the epithelial barrier might be a risk factor for allergen sensitization and asthma. Viral respiratory tract infections are strongly associated with asthma exacerbation, but the effects of respiratory viruses on airway epithelial barrier function are not well understood. Ma...

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Hlavní autoři: Rezaee, Fariba, Meednu, Nida, Emo, Jason A., Saatian, Bahman, Chapman, Timothy J., Naydenov, Nayden G., De Benedetto, Anna, Beck, Lisa A., Ivanov, Andrei I., Georas, Steve N.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3273326/
https://ncbi.nlm.nih.gov/pubmed/21996340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2011.08.035
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