Natural antioxidant dihydroxybenzyl alcohol blocks ritonavir-induced endothelial dysfunction in porcine pulmonary arteries and human endothelial cells

BACKGROUND: Patients with HIV have an increased incidence of pulmonary artery hypertension. This study was designed to determine if the naturally occurring antioxidant dihydroxybenzyl alcohol (DHBA) could counteract the deleterious effects of ritonavir (RTV), an HIV-protease inhibitor known to impai...

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Bibliographische Detailangaben
Hauptverfasser: Weakley, Sarah M., Jiang, Jun, Lü, Jianming, Wang, Xinwen, Lin, Peter H., Yao, Qizhi, Chen, Changyi
Format: Artigo
Sprache:Inglês
Veröffentlicht: International Scientific Literature, Inc. 2011
Schlagworte:
Basic Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3273316/
https://ncbi.nlm.nih.gov/pubmed/21873935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.881926
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