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Decreased Xylitol Formation during Xylose Fermentation in Saccharomyces cerevisiae Due to Overexpression of Water-Forming NADH Oxidase

The recombinant xylose-fermenting Saccharomyces cerevisiae strain harboring xylose reductase (XR) and xylitol dehydrogenase (XDH) from Scheffersomyces stipitis requires NADPH and NAD(+), creates cofactor imbalance, and causes xylitol accumulation during growth on d-xylose. To solve this problem, nox...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zhang, Guo-Chang, Liu, Jing-Jing, Ding, Wen-Tao
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3272991/
https://ncbi.nlm.nih.gov/pubmed/22156411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.06635-11
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