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Determination of Minimum Alveolar Concentration for Isoflurane and Sevoflurane in a Rodent Model of Human Metabolic Syndrome

BACKGROUND: Morbid obesity affects the pharmacokinetics and pharmacodynamics of anesthetics, which may result in inappropriate dosing. We hypothesized that obesity significantly alters the minimum alveolar concentration (MAC) for isoflurane and sevoflurane. In order to test this hypothesis, we used...

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Autores principales: Pal, Dinesh, Walton, Meredith E., Lipinski, William J., Koch, Lauren G., Lydic, Ralph, Britton, Steve L., Mashour, George A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3272881/
https://ncbi.nlm.nih.gov/pubmed/22167771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1213/ANE.0b013e31823ede22
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