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Rapid and adaptive evolution of MHC genes under parasite selection in experimental vertebrate populations

The genes of the major histocompatibility complex are the most polymorphic genes in vertebrates, with more than 1,000 alleles described in human populations. How this polymorphism is maintained, however, remains an evolutionary puzzle. Major histocompatibility complex genes have a crucial function i...

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Detalhes bibliográficos
Main Authors: Eizaguirre, Christophe, Lenz, Tobias L., Kalbe, Martin, Milinski, Manfred
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3272583/
https://ncbi.nlm.nih.gov/pubmed/22233631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms1632
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