The structure of drug-deoxydinucleoside phosphate complex; generalized conformational behavior of intercalation complexes with RNA and DNA fragments.

A 2:2 complex of proflavine and deoxycytidylyl-3', 5'-guanosine has been crystallized and its structure determined by x-ray crystallography. The two dinucleoside phosphate strands form self complementary duplexes with Watson Crick hydrogen bonds. One proflavin is asymmetrically intercalated between...

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Bibliografiske detaljer

Udgivet i:	Nucleic Acids Res
Principais autores:	Shieh, H S, Berman, H M, Dabrow, M, Neidle, S
Format:	Artigo
Sprog:	Inglês
Udgivet:	Oxford University Press 1980
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC327244/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7355129/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/8.1.85
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