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Noxa: at the tip of the balance between life and death
Among all Bcl2 homology domain 3 (BH3)-only proteins known to date, APR/PMAIP1/Noxa, albeit showing weak proapoptotic potential on its own, appears to be crucial in fine-tuning cell death decisions by targeting the prosurvival molecule Mcl1 for proteasomal degradation. This event appears critical fo...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3272398/ https://ncbi.nlm.nih.gov/pubmed/19641509 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.46 |
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