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Drosophila endocytic neoplastic tumor suppressor genes regulate Sav/Wts/Hpo signaling and the c-Jun N-terminal kinase pathway

Genetic screens in the fruit fly Drosophila melanogaster have identified a class of neoplastic tumor suppressor genes (endocytic nTSGs) that encode proteins that localize to endosomes and facilitate the trafficking of membrane-bound receptors and adhesion molecules into the degradative lysosome. Los...

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Autors principals: Robinson, Brian S, Moberg, Kenneth H
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3272291/
https://ncbi.nlm.nih.gov/pubmed/22101275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.23.18243
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