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Transcriptional and Epigenetic Mechanisms of Addiction

Investigations of long-term changes in brain structure and function that accompany chronic exposure to drugs of abuse suggest that alterations in gene regulation contribute importantly to the addictive phenotype. We review multiple mechanisms by which drugs alter the transcriptional potential of gen...

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Détails bibliographiques
Auteurs principaux: Robison, Alfred J., Nestler, Eric J.
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3272277/
https://ncbi.nlm.nih.gov/pubmed/21989194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrn3111
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