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Transcriptional and Epigenetic Mechanisms of Addiction

Investigations of long-term changes in brain structure and function that accompany chronic exposure to drugs of abuse suggest that alterations in gene regulation contribute importantly to the addictive phenotype. We review multiple mechanisms by which drugs alter the transcriptional potential of gen...

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Detalhes bibliográficos
Main Authors: Robison, Alfred J., Nestler, Eric J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3272277/
https://ncbi.nlm.nih.gov/pubmed/21989194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrn3111
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