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The HARE-HTH and associated domains: Novel modules in the coordination of epigenetic DNA and protein modifications

Human ASXL proteins, orthologs of Drosophila Additional sex combs, have been implicated in conjunction with TET2 as a major target for mutations and translocations, leading to a wide range of myeloid leukemias, related myelodysplastic conditions (ASXL1 and ASXL2) and Bohring-Opitz syndrome, a develo...

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Detalhes bibliográficos
Main Authors: Aravind, L, Iyer, Lakshminarayan M
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3272235/
https://ncbi.nlm.nih.gov/pubmed/22186017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.11.1.18475
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