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Anoctamins and gastrointestinal smooth muscle excitability

Interstitial cells of Cajal (ICC) generate electrical pacemaker activity in gastrointestinal (GI) smooth muscles. We investigated whether Tmem16a, which encodes Anoctamin 1 (ANO1), a Ca(2+)-activated Cl(−) channel might be involved in pacemaker activity in ICC. Tmem16a transcripts and ANO1 were expr...

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Détails bibliographiques
Auteurs principaux: Sanders, Kenton M., Zhu, Mei Hong, Britton, Fiona, Koh, Sang Don, Ward, Sean M.
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3272164/
https://ncbi.nlm.nih.gov/pubmed/22002868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/expphysiol.2011.058248
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