Identification of Anti-Malarial Compounds as Novel Antagonists to Chemokine Receptor CXCR4 in Pancreatic Cancer Cells

Despite recent advances in targeted therapies, patients with pancreatic adenocarcinoma continue to have poor survival highlighting the urgency to identify novel therapeutic targets. Our previous investigations have implicated chemokine receptor CXCR4 and its selective ligand CXCL12 in the pathogenes...

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Autores principales: Kim, Joseph, Yip, M. L. Richard, Shen, Xiaoming, Li, Hubert, Hsin, Li-Yu Charlie, Labarge, Samuel, Heinrich, Eileen L., Lee, Wendy, Lu, Jianming, Vaidehi, Nagarajan
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3272047/
https://ncbi.nlm.nih.gov/pubmed/22319600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031004
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