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Binding of mouse VL30 retrotransposon RNA to PSF protein induces genes repressed by PSF: Effects on steroidogenesis and oncogenesis

We describe a mechanism of gene regulation involving formation of a complex between PSF protein and mouse VL30 (mVL30) retrotransposon RNA. PSF represses transcription of the insulin-like growth factor 1 (IGF1)-inducible gene P450scc by binding to an insulin-like growth factor response element (IGFR...

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Autori principali: Song, Xu, Sui, Aiwei, Garen, Alan
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC327197/
https://ncbi.nlm.nih.gov/pubmed/14704271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0307794100
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