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Attenuation of extrinsic signaling reveals the importance of matrix remodeling on maintenance of embryonic stem cell self-renewal

The role of extrinsic factors in maintaining self-renewal of embryonic stem cells (ESCs) has been extensively studied since the cells’ isolation, but the necessity for cell-secreted factors in self-renewal has remained undefined to date. Although it is generally accepted that addition of leukemia in...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Przybyla, Laralynne M., Voldman, Joel
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3271888/
https://ncbi.nlm.nih.gov/pubmed/22215601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1103100109
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