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Attenuation of extrinsic signaling reveals the importance of matrix remodeling on maintenance of embryonic stem cell self-renewal
The role of extrinsic factors in maintaining self-renewal of embryonic stem cells (ESCs) has been extensively studied since the cells’ isolation, but the necessity for cell-secreted factors in self-renewal has remained undefined to date. Although it is generally accepted that addition of leukemia in...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3271888/ https://ncbi.nlm.nih.gov/pubmed/22215601 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1103100109 |
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