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Convergence and error estimation in free energy calculations using the weighted histogram analysis method

The weighted histogram analysis method (WHAM) has become the standard technique for the analysis of umbrella sampling simulations. In this paper, we address the challenges (1) of obtaining fast and accurate solutions of the coupled nonlinear WHAM equations, (2) of quantifying the statistical errors...

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Detalhes bibliográficos
Main Authors: Zhu, Fangqiang, Hummer, Gerhard
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3271861/
https://ncbi.nlm.nih.gov/pubmed/22109354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcc.21989
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