Histone deacetylase inhibitors are potent inducers of gene expression in latent EBV and sensitize lymphoma cells to nucleoside antiviral agents

Induction of EBV lytic-phase gene expression, combined with exposure to an antiherpes viral drug, represents a promising targeted therapeutic approach to EBV-associated lymphomas. Short-chain fatty acids or certain chemotherapeutics have been used to induce EBV lytic-phase gene expression in culture...

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Hlavní autoři: Ghosh, Sajal K., Perrine, Susan P., Williams, Robert M., Faller, Douglas V.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2012
Témata:
Lymphoid Neoplasia
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3271713/
https://ncbi.nlm.nih.gov/pubmed/22160379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-06-362434
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