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The development of an inducible androgen receptor knockout model in mouse to study the postmeiotic effects of androgens on germ cell development

A mouse model with a Sertoli cell (SC)-selective ablation of the androgen receptor (AR)—the SCARKO mouse—demonstrated that the effects of androgens on spermatogenesis depend on the presence of an active AR in SC. This model has been extremely valuable in the study of the effects of androgens on the...

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書誌詳細
主要な著者: Willems, Ariane, De Gendt, Karel, Deboel, Lodewijk, Swinnen, Johannes V, Verhoeven, Guido
フォーマット: Artigo
言語:Inglês
出版事項: Landes Bioscience 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3271646/
https://ncbi.nlm.nih.gov/pubmed/22332118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/spmg.1.4.18740
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