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The development of an inducible androgen receptor knockout model in mouse to study the postmeiotic effects of androgens on germ cell development
A mouse model with a Sertoli cell (SC)-selective ablation of the androgen receptor (AR)—the SCARKO mouse—demonstrated that the effects of androgens on spermatogenesis depend on the presence of an active AR in SC. This model has been extremely valuable in the study of the effects of androgens on the...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Landes Bioscience
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3271646/ https://ncbi.nlm.nih.gov/pubmed/22332118 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/spmg.1.4.18740 |
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