Automated array-based genomic profiling in chronic lymphocytic leukemia: Development of a clinical tool and discovery of recurrent genomic alterations

B cell chronic lymphocytic leukemia (B-CLL) is characterized by a highly variable clinical course. Recurrent chromosomal imbalances provide significant prognostic markers. Risk-adapted therapy based on genomic alterations has become an option that is currently being tested in clinical trials. To sup...

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Dades bibliogràfiques
Autors principals: Schwaenen, Carsten, Nessling, Michelle, Wessendorf, Swen, Salvi, Tatjana, Wrobel, Gunnar, Radlwimmer, Bernhard, Kestler, Hans A., Haslinger, Christian, Stilgenbauer, Stephan, Döhner, Hartmut, Bentz, Martin, Lichter, Peter
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2004
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC327147/
https://ncbi.nlm.nih.gov/pubmed/14730057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0304717101
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