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Synthesis and structure of [(η(6)-p-cymene)Ru(2-anthracen-9-ylmethylene-N-ethylhydrazinecarbothioamide)Cl]Cl; biological evaluation, topoisomerase II inhibition and reaction with DNA and human serum albumin

We have synthesized and evaluated the biological properties of a compound of the type [η(6)-p-cymene)Ru(EtATSC)Cl]Cl (1) where EtATSC = 2-anthracen-9-ylmethylene-N-ethylhydrazinecarbothioamide, a thiosemicarbazone. The complex has been characterized by elemental analysis, spectroscopically (NMR, UV-...

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Detalhes bibliográficos
Main Authors: Beckford, Floyd, Thessing, Jeffrey, Woods, Jason, Didion, Jacob, Gerasimchuk, Nikolay, Gonzalez-Sarrias, Antonio, Seeram, Navindra P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3271380/
https://ncbi.nlm.nih.gov/pubmed/21347491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c1mt00003a
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